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Clinical Studies

What are the benefits of beetroot?
Beet Root powder benefits
22 Amazing Benefits of Beets
Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers
Acute ingestion of beetroot juice increases exhaled nitric oxide in healthy individuals
Beet Root Juice - An Ergogenic Aid for Exercise and the Aging Brain
Dietary beetroot juice - effects on physical performance in COPD patients
Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients
Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise & enhances tolerance to high-intensity exercise in humans
Effect of beetroot juice on lowering blood pressure
Potential Benefits of Beetroot Supplementation in Health & Disease

17 Science-Based Benefits of Cetylated Fatty Acids
Cetyl Myristoleate - A Unique Natural Compound, Valuable in Arthritis conditions
Cetyl Myristoleate Overview
EFFECT OF CETYL MYRISTOLEATE ON THE COURSE OF ARTHRITIC EPISODES IN PATIENTS WITH VARIOUS AUTO
Influences of a dietary supplement and diet regimen on adipocytokines and adiposity in women who are overweight
Journal of Rheumatology 2002
Lubricate Joints with Cetyl Myristoleate
San Diego Clinic Immunological Center Clinical Study On Cetylmyristoleate vs Arthritis
Siemandi Randomized Clinical Trial 1997 on cetylllmyristoleate for arthritic conditions

Chromium Picolinate What Are the Benefits
Anti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and streptozotoci
Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases
Chromium picolinate inhibits cholesterol-induced stimulation of platelet aggregation in hypercholesterolemic rats
Effect of chromium dinicocysteinate on levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects
Metformin versus chromium picolinate in clomiphene citrate-resistant patients with PCOs- A double-blind randomized clinical trial
Possible involvement of corticosterone and serotonin in antidepressant and anti-anxiety
Role of liver fatty acid binding protein in hepatocellular injury- effect of CrPic treatment
The effect of chromium picolinate supplementation on the pancreas and macroangiopathy in type II diabetes mellitus rats

9 Benefits of Coenzyme Q10
Coenzyme Q10 for the treatment of heart failure- a review of the literature
Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging
Coenzyme q10 therapy
CoQ10 antidiabetic mechanisms underlie its positive effect- modulation of insulin and adiponectine receptors, Tyrosine kinase, in insulin resistant-diabetic rats
Effects of CoQ10 Supplementation on Lipid Profiles and Glycemic Control in Patients with Type 2 Diabetes
Genetics of coenzyme q10 deficiency
Low plasma coenzyme Q10 levels as an independent prognostic factor for melanoma progression
The role of oxidative stress and antioxidants in male fertility

9 Impressive Benefits of Folic Acid
Chemoprevention using folic acid for dysplastic lesions of the larynx
Folic acid delays development of atherosclerosis
Folic Acid in Stroke Prevention in Countries without Mandatory Folic Acid Food Fortification
Folic Acid Promotes Wound Healing in Diabetic Mice by Suppression of Oxidative Stress
Maternal folic acid supplementation and dietary folate intake and congenital heart defects

What are fructooligosaccharides and how do they provide digestive
Influence of dietary protein and fructooligosaccharides on fecal fermentative end-products, fecal bacterial populations and apparent total tract digestibility in dogs
Prebiotic Effect of Fructooligosaccharides from Morinda officinalis on Alzheimer's Disease in Rodent Models by Targeting the Microbiota-Gut-Brain Axis

7 Fulvic Acid Minerals Benefits & Uses - Improve Gut, Skin & Brain Health
Complement-fixing activity of fulvic acid from Shilajit and other natural sources
Fulvic Acid Attenuates Resistin-Induced Adhesion of HCT-116 Colorectal Cancer Cells to Endothelial Cells
Investigating the biological properties of carbohydrate derived fulvic acid (CHD-FA) as a potential novel therapy for the management of oral biofilm infections
Microarray analysis of immediate-type allergy in KU812 cells in response to fulvic acid

13 Surprising Benefits of Grape Seed Extract
Anticancer and Cancer Chemopreventive Potential of Grape Seed Extract and Other Grape-Based Products
Grape Seed Extract Inhibits Angiogenesis via Suppression of the Vascular Endothelial Growth Factor Receptor Signaling Pathway
Grape seed procyanidin extract against lung cancer- the role of microrna-106b, bioavailability, and bioactivity
Molecular characterization of the grape seeds extract's effect against chemically induced liver cancer
Nanoparticle delivery of grape seed-derived proanthocyanidins to airway epithelial cells dampens oxidative stress and inflammation
Neuro- and nephroprotective effect of grape seed proanthocyanidin extract against carboplatin and thalidomide
Protective effect of grape seed and skin extract against high-fat diet-induced dyshomeostasis of energetic metabolism in rat lung

Arginine, N-carbamylglutamate, and glutamine exert protective effects against oxidative stress
Effect of L-arginine or L-citrullineoral supplementation on blood pressure & right ventricular function in heart failure patients
Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells
Health Benefits of L-Arginine
Kidney Mass Reduction Leads to L-Arginine Metabolism-Dependent Blood Pressure Increase in Mice
L-arginine Benefits Heart Health & Exercise Performance
L-Arginine Heart Benefits
Randomized trial of amion acid combined with pyusical activity for abdominal fat retuction in overweight adults
Vascular endothelhelium-dependent and Independent Actions of Oleanolic Acid

Citrulline - Benefits
Administration of L-arginine plus L-citrulline or L-citrulline alone successfully retarded endothelial senescence
Citrulline an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
Citrulline increases arginine pools and restores nitrogen balance after massive intestinal resection
Effect of L-arginine or L-citrullineoral supplementation on blood pressure & right ventricular function in heart failure patients

13 Amazing Benefits of Magnesium
9 Evidence-Based Health Benefits of Magnesium
7 Signs You May Be Deficient in Magnesium
Effect of potassium magnesium citrate and vitamin B-6 prophylaxis for recurrent and multiple calcium oxalate and phosphate urolithiasis
Effects of oral magnesium on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease
Magnesium improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep
Magnesium onmetabolic and inflammatory markers, global genomic & proteomic profiling- a randomized, controlled, crossover trial
Magnesium supplementation helps to improve carotid intima media thickness in patients on hemodialysis
Media calcification, low erythrocyte magnesium, altered plasma magnesium, and calcium homeostasis
Metabolic and clinical effects of oral magnesium supplementation in furosemide-treated patients with severe congestive heart failure
Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study
Short-term oral magnesium supplementation suppresses bone turnover in postmenopausal osteoporotic women
The effects of magnesium prophylaxis in migraine without aura

5 Best Benefits of Mucuna Pruriens
A Water Extract of Mucuna pruriens Provides Long-Term Amelioration of Parkinsonism with Reduced Risk for Dyskinesias
Anticataleptic and antiepileptic activity of ethanolic extract of leaves of Mucuna pruriensl
Effect of Mucuna pruriens (Linn) on Sexual Behavior and Sperm Parameters in Streptozotocin-Induced Diabetic Male Rat
Enzyme inhibitory and antioxidant activities of medicinal plants-Potential in the management of hyperglycemia
Evaluation of the anti-diabetic properties of Mucuna pruriens seed Extract
Mucuna pruriens and Its Major Constituent L-DOPA Recover Spermatogenic Loss by Combating ROS
Mucuna pruriens Reduces Stress and Improves the Quality of Semen in Infertile Men
Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens

13 Perilla Oil Benefits
17 Science-Based Benefits of Omega-3 Fatty Acids
Anti-atherosclerotic effects of perilla oil in rabbits fed a high-cholesterol diet
Anti-inflammatory effects of Perilla frutescens in activated human neutrophils through two independent pathways
Circulating omega-3 Fatty acids and neovascular age-related macular degeneration
Colon cancer prevention with a small amount of dietary perilla oil high in alpha-linolenic acid in an animal model
Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina.
Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes.
Historical overview of n 3 fatty acids and coronary heart disease
Maternal Supplementation With Very-Long-Chain n-3 Fatty Acids During Pregnancy & Lactation Augements Children's IQ at 4 years of age
Omega-3 Fatty Acids and Depression-Scientific Evidence and Biological Mechanisms
Omega-3 fattyacids and the treatment of depression
Omega-3 supplementation lowers inflammation and anxiety in medical students
Perilla Oil Supplementation Ameliorates High-Fat -High-Cholesterol Diet Induced Nonalcoholic Fatty Liver Disease in Rats
Role of Omega-3 fatty acids in the etiology, treatment, and prevention of depression
Suppression of hepatic fatty acid synthase by feeding alpha-linolenic acid rich perilla oil lowers plasma triacylglycerol level in rats
The role of n-3 polyunsaturated fatty acids in brain

Potassium is an essential dietary mineral and electrolyte
13 Incredible Benefits of Potassium
Bone disease in medullary sponge kidney and effect of potassium citrate treatment
Effect of Short-Term Supplementation of Potassium Chloride and Potassium Citrate on Blood Pressure in Hypertensives
Effects of Potassium Magnesium Citrate Supplementation on 24-Hour Ambulatory Blood Pressure and Oxidative Stress Marker in Prehypertensive and Hypertensive Subjects
Efficacy of potassium polycitrate on renal stone and microlithiasis predisposed by metabolic disorders
Influence of Hydration and Electrolyte Supplementation on Incidence and Time to Onset of Exercise-Associated Muscle Cramps
POTASSIUM CITRATE DECREASES BONE RESORPTION IN POSTMENOPAUSAL WOMEN WITH OSTEOPENIA
Potassium citrate supplementation results in sustained improvement in calcium balance in older men and women
Potassium contractures in single muscle fibres

What Are the Health Benefits of CoQ10 & Resveratrol
6 Amazing Resveratrol Benefits
Acute Resveratrol Consumption Improves Neurovascular Coupling Capacity in Adults with Type 2 Diabetes Mellitus
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
Inhibition of RAD51 by siRNA and Resveratrol Sensitizes Cancer Stem Cells Derived from HeLa Cell Cultures to Apoptosis
Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases
Protective action of resveratrol in human skin- possible involvement of specific receptor binding sites
Protective effect of resveratrol against pressure overload-induced heart failure
Resveratrol and Diabetes
Resveratrol as a therapeutic agent for Alzheimer's disease
Resveratrol improves diabetic retinopathy possibly through oxidative stress - nuclear factor κB - apoptosis pathway
Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides
Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis
Resveratrol Suppresses the Growth and Enhances Retinoic Acid Sensitivity of Anaplastic Thyroid Cancer Cells
The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling
The occurrence of resveratrol in foodstuffs and its potential for supporting cancer prevention and treatment

Rice Bran Benefits
What Are the Health Benefits of Stabilized Rice Bran
Dietary supplementation with rice bran or navy bean alters gut bacterial metabolism in colorectal cancer survivors.
Rice Bran Metabolome Contains Amino Acids, Vitamins & Cofactors, and Phytochemicals with Medicinal and Nutritional Properties

13 Proven Benefits of Selenium
Antioxidants selenomethionine and D-pantethine decrease the negative side effects of doxorubicin in NL-Ly lymphoma-bearing mice
Interactions of serum copper, selenium, and low density lipoprotein cholesterol in atherogenesis
Selenium in the Immune System
Selenium, the Thyroid, and the Endocrine System

7 Amazing Benefits of Vitamin B12
Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1
Higher prevalence of metformin-induced vitamin B12 deficiency
Hyperhomocysteinemia and neurologic disorders- a review
Neuroenhancement with vitamin B12-underestimated neurological significance
Relationship between metformin use, vitamin B12 deficiency, in patients with type 2 diabetes
Vitamin B12 deficiency in relation to functional disabilities
Vitamin B12 rich diet improves brain, neurotrophins and cognition
Vitamin B12 supplementation in treating major depressive disorder- a randomized controlled trial
Vitamin B 12 dependent taurine synthesis regulates growth and bone mass

15 Amazing Vitamin C
Ascorbic Acid and the Brain - Rationale for the Use against Cognitive Decline
Association between vitamin C intake and lung cancer
Association of dietary vitamin C and e intake and antioxidant enzymes in type 2 diabetes mellitus patients
Influence of ascorbic acid supplementation on type 2 diabetes mellitus
Metabolomic alterations in human cancer cells by vitamin C-induced oxidative stress
Pharmacologic ascorbic acid concentrations selectively kill cancer cells
Vitamin C deficiency in the brain impairs cognition, increases amyloid accumulation and deposition, and oxidative stress
Vitamin C in the treatment and-or prevention of obesity
Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

4 Surprising Benefits of Vitamin D3
A 12-week double-blind randomized clinical trial of vitamin D3 on body fat mass in healthy overweight & obese women
Calcium plus vitamin D3 supplementation facilitated fat loss in overweight and obese college students
Higher Predicted Vitamin D Status Is Associated With Reduced Risk of Crohn's Disease
Low Vitamin D Status- A Contributing Factor in the Pathogenesis of congestive Heart failure
Major Electrocardiographic Abnormalities and 25-Hydroxy Vitamin D Deficiency
Study Link Between Vitamin D and Dementia Risk Confirmed
Vitamin D and cancer - Clinical aspects
Vitamin D in food and supplements
Vitamin D receptor gene polymorphism- association with Crohn's disease susceptibility
Vitamin D3 Higher Doses Reduce Risk of Common Health Concerns

14 Amazing Benefits of Vitamin E
DHA-PC and PSD-95 decrease after loss of synaptophysin & before neuronal loss in patienta with Alzheimer's disease
Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner
Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis
The Vitamin Found to Destroy Cancer Cells
This Vitamin is Vital for Preserving Brain Health
Vitamin E Succinate Is a Potent Novel Antineoplastic Agent with with Slecttivity & Cooperativity with Tumor Necosis Factor